As with all great writing, you can't find just one answer to the question of meaning in "To Kill a Mockingbird." However, there are ideas associated with the bird which are very important in the novel.
If you think about where it is first mentioned, Atticus is giving his children permission to shoot destructive birds, like jays, but adds "Remember, it's a sin to kill a mockingbird." Atticus, a liberal, tolerant man, doesn't use the word "sin" lightly. He explains it is because mockingbirds harm nobody, they just make lovely music. From this we can get the idea that Harper Lee chose the title so we keep this principle in mind - it is always wrong to harm those who have not harmed us. This idea can be applied to the treatment of specific characters in the novel - especially Boo Radley and Tom Robinson - and by extension to the glaring racial injustices and cruelties which are practised every day in Atticus's community. When he defends Tom in the trial, for instance, he is trying to prevent the townspeople from "killing a mockingbird" - that is, condemning an innocent man to death for no reason at all except prejudice.
If you think about where it is first mentioned, Atticus is giving his children permission to shoot destructive birds, like jays, but adds "Remember, it's a sin to kill a mockingbird." Atticus, a liberal, tolerant man, doesn't use the word "sin" lightly. He explains it is because mockingbirds harm nobody, they just make lovely music. From this we can get the idea that Harper Lee chose the title so we keep this principle in mind - it is always wrong to harm those who have not harmed us. This idea can be applied to the treatment of specific characters in the novel - especially Boo Radley and Tom Robinson - and by extension to the glaring racial injustices and cruelties which are practised every day in Atticus's community. When he defends Tom in the trial, for instance, he is trying to prevent the townspeople from "killing a mockingbird" - that is, condemning an innocent man to death for no reason at all except prejudice.